How does Vidalista selectively inhibit phosphodiesterase type 5 (PDE5) in the corpus cavernosum?

by Guest » Thu Apr 25, 2024 05:39 am
Guest

Vidalista, also known as Tadalafil, selectively inhibits phosphodiesterase type 5 (PDE5) in the corpus cavernosum by specifically targeting this enzyme. PDE5 is responsible for breaking down cyclic guanosine monophosphate (cGMP), which plays a crucial role in regulating blood flow to the penis. When PDE5 is inhibited, cGMP levels increase, leading to smooth muscle relaxation and vasodilation in the corpus cavernosum, which enhances blood flow into the penis and facilitates an erection. Tadalafil, the active ingredient in Vidalista, works by binding to the active site of PDE5, thereby preventing it from breaking down cGMP. This allows cGMP to accumulate, promoting relaxation of smooth muscle cells and increasing blood flow to the penis during sexual stimulation. It's important to note that Vidalista doesn't directly cause an erection but enhances the natural process of arousal, allowing for improved erectile function in men with erectile dysfunction.

Add your comment

Image CAPTCHA
Enter the characters shown in the image.