Filitra, which contains vardenafil (a phosphodiesterase type 5 inhibitor), is used to treat erectile dysfunction (ED). One of the key reasons Filitra may have a longer duration of effect compared to some other ED drugs (like sildenafil or tadalafil) lies in its unique formulation and pharmacokinetics. Reasons for Filitra's Longer Duration: Pharmacokinetics: Vardenafil, the active ingredient in Filitra, has a longer half-life compared to some other PDE5 inhibitors, such as sildenafil (Viagra). The half-life of vardenafil is typically about 4-5 hours, allowing it to remain active in the system for a longer period. This is why Filitra may provide effects for 4 to 6 hours, sometimes even longer. Long-Lasting Effects: While sildenafil (Viagra) lasts around 4 hours, Filitra’s effects can persist for up to 6 hours or more, giving users more flexibility in terms of timing sexual activity. However, it doesn’t mean that an erection will be sustained for this period—sexual stimulation is still necessary for the drug to work effectively. Speed of Onset and Duration: Filitra tends to start working about 30 to 60 minutes after ingestion, which is similar to other PDE5 inhibitors. However, the longer duration comes from the way vardenafil is metabolized in the body. The drug’s sustained action gives it an advantage over some alternatives, offering a broader window for sexual activity. Metabolism: Vardenafil has a relatively moderate rate of metabolism, which may contribute to its prolonged action compared to drugs like sildenafil. It’s processed more slowly in the liver, extending its effects without leading to a rapid decline in efficacy. Comparison to Other ED Drugs: Sildenafil (Viagra): Typically lasts for 4 hours, so Filitra’s longer duration offers more time for sexual activity. Tadalafil (Cialis): Known for its 36-hour duration, which is significantly longer than Filitra, but it may take a bit longer to start working compared to Filitra.
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