Ceftriaxone injection, a cephalosporin antibiotic, requires strict precautions to ensure safe administration. Avoid use in neonates under 28 days receiving calcium-containing IV solutions, as ceftriaxone calcium precipitates can form in lungs or kidneys, posing fatal risks. Do not mix with calcium based diluents like Ringer’s solution. Administer cautiously in patients with penicillin or cephalosporin allergies due to potential cross-hypersensitivity. Monitor for severe side effects, including diarrhea, seizures, or hemolytic anemia. Ensure proper reconstitution by a reliable ceftriaxone supplier and check for discoloration or particles. Follow dosage guidelines, avoid overuse, and maintain adequate hydration to prevent renal complications.
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