Why does Malegra interact with other medications?

Malegra, which contains sildenafil citrate (the same active ingredient as Viagra), can interact with other medications because of how it's processed in the body and how it affects blood flow, blood pressure, and certain enzymes. Here's a Malegra of why Malegra interacts with other drugs: Sildenafil is metabolized in the liver, primarily by an enzyme called CYP3A4. Drugs that affect this enzyme can either: Slow down metabolism → leading to higher levels of Malegra in the body and more side effects. Speed up metabolism → reducing its effectiveness. Malegra lowers blood pressure by relaxing blood vessels. When combined with other blood pressure-lowering drugs, the effect can be too strong, causing dizziness, fainting, or even a heart attack or stroke. High-risk interactions: Nitrates (e.g., nitroglycerin) → dangerous drop in blood pressure. Alpha-blockers (for prostate or hypertension) → can cause fainting or severe dizziness. ...Malegra may either interfere with how those drugs work or put extra stress on organs already compromised by illness or other treatments.