Cenforce 50, containing sildenafil citrate, may interact with various antidepressants, potentially leading to adverse effects. Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine or sertraline can raise serotonin levels, and when combined with sildenafil, may increase the risk of serotonin syndrome—a rare but serious condition.
Tricyclic antidepressants and monoamine oxidase inhibitors (MAOIs) can affect blood pressure, and since sildenafil also lowers blood pressure, the combination might cause dizziness, fainting, or hypotension. Additionally, some antidepressants inhibit liver enzymes (like CYP3A4), which can slow the metabolism of Cenforce 50mg, increasing its levels and side effects such as headaches, flushing, or prolonged erections. Always consult a doctor before combining them.
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